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Symbiosis™ Pro

SymbiosisPro_1Request Pricing

$145k – $175k

Symbiosis™ Pro is Spark Holland’s unique solution for integrated on-line SPE-LC-MS automation (XLC-MS). The system offers large flexibility in processing different types of samples selecting one of the three fully automated operational modes LC-MS (direct LC without SPE); XLC-MS (on-line SPE coupled to LC-MS); AMD (advanced method development).

System Components

ACE™ Automatic Cartridge Exchanger

ACE_1Combining the best of the on-line and off-line SPE worlds. Off-line SPE (Solid Phase Extraction) provides cartridge refreshment for every sample, avoiding the risk of retention change and carry-over.

Reliance™

Reliance_1The introduction of modern fast detection and data acquisition methods has caused a significant increase in the number of samples processed in laboratories.

HPD™ Mix

HPD_mixTraditional volumetric dispensers are designed for pipetting reagents or samples into vials or wells at ambient pressure or a few Bar at most. on-line volumetric reagent delivery however, may require the ability to introduce reagents into a system with a high working pressure.

SPH1240™ Pumpset

Pump_1Ultra high pressure pumps enable use of longer columns, higher flow rates and smaller particles. The optimum combination of these parameters may vary largely with the requirements of your assay.

Analyst Driver

iChrom_Product_AnalystThe Analyst driver can control different Spark configurations like the On-line SPE systems and the LC sets.

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SparkLink

iChrom_Product_SparkLinkThe SparkLink sofware controls all the Spark modules and can run independent from the the data-acquisition software.

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Specifications

Symbiosis™ Pro is Spark Holland’s unique solution for integrated on-line SPE-LC-MS automation (XLC-MS). The system offers large flexibility in processing different types of samples selecting one of the three fully automated operational modes LC-MS (direct LC without SPE); XLC-MS (on-line SPE coupled to LC-MS); AMD (advanced method development). The combination of a highly selective on-line SPE and a superb top line autosampler makes this dedicated high throughput PRO system the best tool for direct injection of raw biological samples. The zero sample loss injection mode offers the best possible results even when there is little sample volume available (5 µL injection out of a 8 µL sample).

All Symbiosis™ on-line SPE Systems process multiple batches/assays fast and reliably, with the highest analytical performance, fully unattended. They also have all the tools to perform method development using a systematic approach which generates a working on-line SPE method in just a few days. These versatile workhorses are a safe investment and allow you to perform more projects with the highest assay performance in the same time and use the full MS capacity to the lab’s economical benefit.

Superb Analytical Performance

  • Generic templates for Acidic, Basic and Neutral compounds
  • Instant feedback during method optimizing
  • Test more variables in less time
  • No more compromising assay quality

Improve Workflow

  • Simultaneous sample prep & LC
  • Automated solvent mixing
  • Multi assay processing
  • Integrated software control in Analyst™
  • More samples per day per analyst

Cut Method Development

  • 100% fresh High Performance sorbent for each sample
  • 100% reproducible and traceable assay conditions for each sample
  • Analyte enrichment & peak focusing for highest assay sensitivity
  • Multi dimensional SPE (mXLC)
  • Superb Analytical Performance

Symbiosis™ Pro consists of the following modules:

  • Reliance autosampler
  • SPH1240 gradient pumpset
  • ACE dual clamp system
  • (2) High Pressure Dispensers
  • Integrated systems control with Analyst driver, Masslynx driver, or Sparklink
  • Solvent organizers
  • Cart for movement in the lab